Free Ebook Charisma, by Jeanne Ryan

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Charisma, by Jeanne Ryan

Charisma, by Jeanne Ryan


Charisma, by Jeanne Ryan


Free Ebook Charisma, by Jeanne Ryan

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Charisma, by Jeanne Ryan

From School Library Journal

Gr 8 Up—Aislyn is cripplingly shy: she's very smart and could have won the state science fair with her research on gene therapies, if only she'd been able to bring herself to talk to the judges about it. She'd love to talk to people and advocate for gene therapies as a treatment for various illnesses, like her brother's cystic fibrosis, but she freezes up and can't get words out. So when a researcher offers her a chance to overcome her social anxieties with an experimental gene therapy, Aislyn jumps at the chance. Her new gregarious self isn't afraid to talk to the boy she's been crushing on, or go to parties, or be a normal teenager. But some other teens have been given the treatment, too, and have collapsed. Then the symptoms start appearing in people who haven't had the therapy. Charisma may not be the answer Aislyn was hoping for. Not a far step from Ned Vizzini's Be More Chill (Hyperion, 2004), this novel features more current, realistic medical technology. The science is explained well enough for non-scientist readers to understand, and gives teens much to think about regarding medical ethics and experimentation. Aislyn's relationship with her boyfriend is chaste by necessity (so she doesn't spread the virus), but there are some mild suggestions of more mature desires. An adequate choice for medium to larger collections.—Brandy Danner, Perkins School for the Blind, Watertown, MA

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Review

"...this fast-paced and edgy novel has enough thrills, romance, and family drama to please a wide audience. This Robin Cook–like thriller zips along at breakneck speed to a satisfying conclusion."—Booklist"Ryan (Nerve) offers a cautionary tale about the perils of designer genetics and what happens when scientists' aspirations get ahead of ethics. Her take on the topic is fresh and intriguing."—Publishers Weekly"Suspense balances with discussions of bioethics for a provocative and entertaining read. A sympathetic protagonist combines with intriguing medical possibility for a solid thriller."—Kirkus Reviews"Charisma by Jeanne Ryan is at its best when it gets technical. Considering Ryan has a PHD and has worked with youth development programs and social workers, it’s obvious she knows what she talking about."—Hypable"Not a far step from Ned Vizzini’s Be More Chill...The science is explained well enough for non-scientist readers to understand, and gives teens much to think about regarding medical ethics and experimentation."—School Library Journal "The science is both sharp and accessible here, and readers will get a sense of the nuances and messiness of genetic alterations while staying in Aislyn’s world."—BCCB

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Product details

Age Range: 12 and up

Grade Level: 7 - 9

Hardcover: 384 pages

Publisher: Dial Books (March 3, 2015)

Language: English

ISBN-10: 0803739664

ISBN-13: 978-0803739666

Product Dimensions:

5.8 x 1.2 x 8.5 inches

Shipping Weight: 1.2 pounds

Average Customer Review:

4.2 out of 5 stars

20 customer reviews

Amazon Best Sellers Rank:

#89,675 in Books (See Top 100 in Books)

Meet Aislyn Hollings, a girl who gives the phrase "cripplingly shy" a whole new spin. She wants to speak up: at the school science fair to promote her excellent project, or at a party where a guy who's obviously into her is trying to start a conversation. But she can't--she'll have a panic attack. Over and over, she watches her social hopes go down in flames of devastating embarrassment.Then she gets the chance of a lifetime--the opportunity to try a new, hush-hush gene therapy that will change her into the sparkling personality she's always wanted to be. Things are great at first, even when she finds out some other kids may have received the same therapy. And then some of them start to have unanticipated, and very bad, side effects. Is Aislyn next? More importantly, can she stop this before it's too late?Charisma is a thoughtful YA thriller from sophomore author Jeanne Ryan (author of Nerve). Most teens, and many adults, want to change something about the way they are. But now, when it seems those changes are possible, how many risks should we take, and what are good reasons for those risks? This book looks at those questions, as well as other teen themes like friendship, loyalty, and popularity. There's also some excellent handling of the fear-driven bigotry some people level at those who are sick, or just different.But just because this book has themes doesn't mean it's boring! I read Charisma in a couple of sittings--the plot took so many exciting turns, I couldn't wait to find out what would happen next. It's firmly in the PG category; I recommend it for any teenager curious about science and ethics, or about herself and her own personality. Five stars!

CHARISMA is a fascinating, chilling and immensely entertaining story that invites readers into a world where an untested gene therapy drug promises amazing results but unbeknownst to its recipients comes at a deadly price. It’s a story that reveals a likely and not-so-far-off future where one’s personality can be radically altered with a single injection. It’s a thought-provoking and gripping and utterly compelling read that will have readers debating the pros and cons of the scientific advancement.When Aislyn Hollings is offered the opportunity to be a test subject for Charisma, a gene enhancement drug that is guaranteed to be life-changing, she is eager to accept. Her debilitating shyness has kept her from living the life she wants and she’s desperate to be someone who is not afraid of everything and everyone all of the time.But when she starts to suspect that she’s not the only one to have been given the dose, or even the first one, her enthusiasm begins to wane. That is, until she finds herself becoming more confident, taking more risks, being more social, feeling more normal.However, when some of the people she believes had their personalities altered by Charisma start getting sick and falling into comas, and the doctor who administered the dose stops responding to her texts and calls, Aislyn decides to break her silence, find out who else might be at risk, and begin a frantic search for a way to reverse the effects before the same thing that happened to them happens to her.Jeanne Ryan penned an absolutely thrilling and heartbreaking and riveting story with a heroine who is incredibly sympathetic and smart and – with the help of Charisma – determined. Her story offers food for thought about the merits of gene therapy, about the risks, about the potential for its use in non-essential treatments, about its potential for use in life-saving situations. And it does so in a way that is engaging and interesting and hugely exciting.CHARISMA is filled with twists and turns, frightening and tragic outcomes, captivating and likable characters, and appealing between-the-chapter tidbits. It is a suspenseful page-turner that combines science that is not entirely fictional, mystery and romance into a story that is positively enthralling.It is a provocative read that will prompt discussion and debate and will keep readers thinking about it long after the story’s end.

I promise no spoilers, but nevertheless must add that the novel, Charisma, concludes in a most satisfying manner, both from the standpoint of the story, which was compelling, as well as the science presented, which was accurate and 21st Century from page 1 to page 374 (including the Author's Note).Although the book was a "page turner," my schedule forced me to read it over a three-day span. Being written in the first person, it provided an almost chilling peek into the personality and neuroses of Aislyn the young protagonist who, to overcome her teenage anxiety, allows herself to be injected with a gene therapeutic drug that "works" essentially overnight. The state of mind (and more) into which Aislyn finds herself is both exhilarating and eye-opening (as in the "third eye" sense).Both the lead up to and aftermath of her one time dose of Charisma provided me with an in-depth view of a transformation that was, quite frankly, chilling. I felt Aislyn's anxieties prior to the transformation and her growing concerns after the transformation as she became increasingly concerned about some of the drug's apparent side effects. Many very real concerns about gene therapy were unveiled as well as some of its potential benefits.The writing was crisp and to the point. The story line was brisk and entertaining. No doubt, this novel will be made into a major motion picture, and I can only hope that the serious points highlighted will be dramatized without dulling the "thriller" aspect of this outstanding five star novel.

I could not put CHARISMA down! I read this book in two sittings and was anticipating the end and making predictions throughout. I loved that I was wrong sometimes because of the unexpected turns the book took. Those unexpected twists made it even more enjoyable and challenged me to read carefully as the suspense built and my anticipation increased. I find gene therapy an interesting topic, especially all of the good that may come from it, but would not have time on my own to research it. Having that wrapped up in a fun novel with likable real characters made the book both a novel and a scientific journey. Thanks for another thought-provoking book, Jeanne Ryan!

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